Partners
TRAIIL-4-life is a multidisciplinary and multinational consortium with currently nine researchers and three SMEs from seven ERA countries.
ANYO Labs
ANYO Labs is a new SME (established in December 2022 in Göteborg, Sweden) that develops and utilizes Artificial Intelligence (AI) and Machine Learning (ML) tools for highly accurate and rapid drug screening and de novo drug discovery. The drug discovery tool i-TripleD has attracted significant attention and is already applied in several drug discovery projects in collaboration with academic and industrial partners. In addition, the company has developed novel protein interaction network software as well as ML-based tools for determining accurate ADMET properties and drug-drug interactions. ANYO Labs was included in the Top100 list by the Royal Swedish Academy of Engineering Sciences (IVA) 2023 and has won several awards during its first year.
Dr. Erika Balint
Assistant Professor at the Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (Budapest, Hungary). Dr. Balint’s main research interests are organic chemical synthesis, microwave, and green chemistry, including the synthesis of biologically active heterocyclic compounds. She received several awards, including the ‘Women in Science Excellence Award’ (Association of Hungarian Women in Science) and ‘New National Excellence Programme’ (Ministry of Human Capacities). Dr. Balint is a founding member of the ‘Hungarian Young Academy’ and is actively involved in the academy’s public outreach and engagement activities.
COVALAB SAS
The SME COVALAB is a leader in the production and chemical modification of biomaterials (antibodies, nanobodies), including antibody-drug conjugations located in Bron, France.
Dr. Said El Alaoui
Dr. El Alaoui is the Chief Executive Officer of COVALAB and a senior scientist with long-standing expertise in biochemistry, chemistry, and immunology. He is an expert in antibody engineering and immunotherapy and his research focus on cancer research and transglutaminase research.
e-NIOS
An SME that specialises on in silico analysis of -omics data using in computational and systems biology, bioinformatics, computational genomics, machine learning, biostatistics, and dynamic data visualization. e-NIOS is located in Athens, Greece.
Dr. Leif Eriksson
Professor at the Department of Chemistry and Molecular Biology, University of Goteborg (Goteborg, Sweden). Dr. Eriksson runs a large, international research group in computational biochemistry, specializing in modelling protein structures, simulation of protein-protein interactions, and in silico drug development, in particular via Machine Learning (ML) tools, for de novo drug design.
Dr. Philippe Krebs
Associate Professor at the Institute of Tissue Medicine and Pathology, University of Bern (Bern, Switzerland). Dr. Krebs’ laboratory is working on the role of inflammation in cancer development and its pathophysiology, as well as immunopathology in general, using mouse models of disease and patient-derived samples.
Dr. Olivier Micheau
Research Director at the INSERM UMR1231 CTM Center for Translational Medicine Dijon (France). Dr. Micheau heads the DeSCarTes team (Death domain-containing signal transduction and cancer Therapies). He is an expert in TNF/TRAIL biology, with a particular focus on signal transduction, membrane receptor assembly and signalling. With his team and collaborators, he aims at translating TRAIL or TRAIL-derivatives to the clinic.
Dr. Duygu Sag
Associate Professor at the Department of Medical Biology, Faculty of Medicine, Dokuz Eylul University; and Research Group Leader at the Izmir Biomedicine and Genome Center (IBG) (Izmir, Turkey). Dr. Sag’s laboratory is working on the mechanisms of macrophage polarization in cancer. Dr. Sag won the international UNESCO/L’Oreal ‘Rising Talent Award’ in 2018 as one of 15 women worldwide and became subsequently elected member of UNESCO Turkey.
Dr. Eva Szegezdi
Senior Research Lecturer in Cancer Biology at the Apoptosis Research Centre and Director of the Blood Cancer Network Ireland (BCNI), University of Galway (Galway, Ireland). Dr. Szegezdi’s research focuses on the molecular wiring of cancer cells and the tumour-microenvironment driving drug resistance utilizing systems biology approaches (e.g. cancer genomics, single-cell transcriptomics) with the ultimate goal of genetically engineering immune cells for anti-cancer immunotherapy. Dr. Szegezdi was the project coordinator of the DISCOVER project.
Dr. Gerhard Wingender
Research Group Leader at the Izmir Biomedicine and Genome Center (IBG) (Izmir, Turkey). Dr. Wingender’s laboratory works on the role of innate-like T cells in the context of cancer, autoimmune and lung diseases using flow cytometry, advanced functional in vitro T cell assays, and in vivo mouse models. Dr. Wingender is the project coordinator of the ongoing CHIRON project.
Previous partners
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Apofas Biotech (Rennes, France; ceased operations).
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Cell Stress Discoveries Limited (Galway, Ireland; https://cellstressdiscoveries.com).
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Dr. Matthieu LeGallo: Research Group Leader at the University of Rennes (France), Oncogenesis Stress Signaling - Inserm U1242. LinkedIn: www.linkedin.com/in/matthieu-le-gallo-b3b4bb46.
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Dr. Patrick Legembre: Director of Research at the University of Limoges (Limoges, France). LinkedIn: www.linkedin.com/in/patrick-legembre-86566439.
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Dr. Afshin Samali: Professor at the University of Galway (Galway, Ireland). LinkedIn: www.linkedin.com/in/apoptosis.
We gratefully acknowledge the ongoing funding and support by the following organizations:
European Commission (EC)
European Molecular Biology Organization (EMBO)
Marie Curie Alumni Association (MCAA)
TÜBITAK (Scientific and Technological Research Institution of Turkey)